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constant current linear stimulus isolator  (Digitimer North America LLC)


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    Digitimer North America LLC constant current linear stimulus isolator
    Constant Current Linear Stimulus Isolator, supplied by Digitimer North America LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/constant current linear stimulus isolator/product/Digitimer North America LLC
    Average 90 stars, based on 1 article reviews
    constant current linear stimulus isolator - by Bioz Stars, 2026-04
    90/100 stars

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    Fig. 10. DBS targeted at the dorsal part of the ventral striatum (dVS) induces a significantly higher percentage signal change compared to intermittent periods of no <t>stimulation</t> in the nucleus accumbens of awake rats. A significant dif ference in percentage signal change in the chosen ROI, the nucleus accumbens (NAc), was found when comparing the DBS ON periods with DBS OFF periods in a group of 6 awake rats. Signal intensity was extracted from the data using featquery (FMRIB Software Library 6.0) with the nucleus accumbens as ROI, from each animal, and the percentage signal change was calculated for DBS ON and the latter half of the DBS OFF periods relative to baseline. A paired sample t-test was performed on the percentages signal change of the DBS ON versus the DBS OFF periods. Mean + SD, *** - p = 0.001.
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    Fig. 10. DBS targeted at the dorsal part of the ventral striatum (dVS) induces a significantly higher percentage signal change compared to intermittent periods of no <t>stimulation</t> in the nucleus accumbens of awake rats. A significant dif ference in percentage signal change in the chosen ROI, the nucleus accumbens (NAc), was found when comparing the DBS ON periods with DBS OFF periods in a group of 6 awake rats. Signal intensity was extracted from the data using featquery (FMRIB Software Library 6.0) with the nucleus accumbens as ROI, from each animal, and the percentage signal change was calculated for DBS ON and the latter half of the DBS OFF periods relative to baseline. A paired sample t-test was performed on the percentages signal change of the DBS ON versus the DBS OFF periods. Mean + SD, *** - p = 0.001.
    Constant Current Linear Stimulus Isolator, supplied by Digitimer North America LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/constant current linear stimulus isolator/product/Digitimer North America LLC
    Average 90 stars, based on 1 article reviews
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    Fig. 10. DBS targeted at the dorsal part of the ventral striatum (dVS) induces a significantly higher percentage signal change compared to intermittent periods of no <t>stimulation</t> in the nucleus accumbens of awake rats. A significant dif ference in percentage signal change in the chosen ROI, the nucleus accumbens (NAc), was found when comparing the DBS ON periods with DBS OFF periods in a group of 6 awake rats. Signal intensity was extracted from the data using featquery (FMRIB Software Library 6.0) with the nucleus accumbens as ROI, from each animal, and the percentage signal change was calculated for DBS ON and the latter half of the DBS OFF periods relative to baseline. A paired sample t-test was performed on the percentages signal change of the DBS ON versus the DBS OFF periods. Mean + SD, *** - p = 0.001.
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    Fig. 10. DBS targeted at the dorsal part of the ventral striatum (dVS) induces a significantly higher percentage signal change compared to intermittent periods of no <t>stimulation</t> in the nucleus accumbens of awake rats. A significant dif ference in percentage signal change in the chosen ROI, the nucleus accumbens (NAc), was found when comparing the DBS ON periods with DBS OFF periods in a group of 6 awake rats. Signal intensity was extracted from the data using featquery (FMRIB Software Library 6.0) with the nucleus accumbens as ROI, from each animal, and the percentage signal change was calculated for DBS ON and the latter half of the DBS OFF periods relative to baseline. A paired sample t-test was performed on the percentages signal change of the DBS ON versus the DBS OFF periods. Mean + SD, *** - p = 0.001.
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    Fig. 10. DBS targeted at the dorsal part of the ventral striatum (dVS) induces a significantly higher percentage signal change compared to intermittent periods of no <t>stimulation</t> in the nucleus accumbens of awake rats. A significant dif ference in percentage signal change in the chosen ROI, the nucleus accumbens (NAc), was found when comparing the DBS ON periods with DBS OFF periods in a group of 6 awake rats. Signal intensity was extracted from the data using featquery (FMRIB Software Library 6.0) with the nucleus accumbens as ROI, from each animal, and the percentage signal change was calculated for DBS ON and the latter half of the DBS OFF periods relative to baseline. A paired sample t-test was performed on the percentages signal change of the DBS ON versus the DBS OFF periods. Mean + SD, *** - p = 0.001.
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    Fig. 10. DBS targeted at the dorsal part of the ventral striatum (dVS) induces a significantly higher percentage signal change compared to intermittent periods of no <t>stimulation</t> in the nucleus accumbens of awake rats. A significant dif ference in percentage signal change in the chosen ROI, the nucleus accumbens (NAc), was found when comparing the DBS ON periods with DBS OFF periods in a group of 6 awake rats. Signal intensity was extracted from the data using featquery (FMRIB Software Library 6.0) with the nucleus accumbens as ROI, from each animal, and the percentage signal change was calculated for DBS ON and the latter half of the DBS OFF periods relative to baseline. A paired sample t-test was performed on the percentages signal change of the DBS ON versus the DBS OFF periods. Mean + SD, *** - p = 0.001.
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    Fig. 10. DBS targeted at the dorsal part of the ventral striatum (dVS) induces a significantly higher percentage signal change compared to intermittent periods of no stimulation in the nucleus accumbens of awake rats. A significant dif ference in percentage signal change in the chosen ROI, the nucleus accumbens (NAc), was found when comparing the DBS ON periods with DBS OFF periods in a group of 6 awake rats. Signal intensity was extracted from the data using featquery (FMRIB Software Library 6.0) with the nucleus accumbens as ROI, from each animal, and the percentage signal change was calculated for DBS ON and the latter half of the DBS OFF periods relative to baseline. A paired sample t-test was performed on the percentages signal change of the DBS ON versus the DBS OFF periods. Mean + SD, *** - p = 0.001.

    Journal: Journal of neuroscience methods

    Article Title: Animal studies in clinical MRI scanners: A custom setup for combined fMRI and deep-brain stimulation in awake rats.

    doi: 10.1016/j.jneumeth.2021.109240

    Figure Lengend Snippet: Fig. 10. DBS targeted at the dorsal part of the ventral striatum (dVS) induces a significantly higher percentage signal change compared to intermittent periods of no stimulation in the nucleus accumbens of awake rats. A significant dif ference in percentage signal change in the chosen ROI, the nucleus accumbens (NAc), was found when comparing the DBS ON periods with DBS OFF periods in a group of 6 awake rats. Signal intensity was extracted from the data using featquery (FMRIB Software Library 6.0) with the nucleus accumbens as ROI, from each animal, and the percentage signal change was calculated for DBS ON and the latter half of the DBS OFF periods relative to baseline. A paired sample t-test was performed on the percentages signal change of the DBS ON versus the DBS OFF periods. Mean + SD, *** - p = 0.001.

    Article Snippet: Both implanted electrodes were connected to a digital stimulator (DS8000, World Precision Instruments, Berlin, Germany) through constant current digital linear stimulation isolators (DSL100, World Precision Instruments, Berlin, Germany) with carbon fiber wires (CPVC4050, 18 American wire gauge, 1.0 mm diameter, 3000 strands, World Precision Instruments, Berlin, Germany).

    Techniques: Software